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It is estimated that about 26 million animals each year are used for scientific and commercial testing in the United States alone. Animals are used for developing medical treatments, determining toxicity of certain produce, checking safety of materials destined for human use or other biomedical, commercial or health care uses. Proponents say that it allowed for the development of life-saving treatments for both humans and animals and that there are no alternatives for adequately researching complete living organisms. Opponents on the other hand say that it is cruel and inhumane and that alternatives are present to replace animal testing. Also the difference between animals and humans would lead to incomparable results.