# -----Greetings from the fractal space---- http://blogs.discovermagazine.com/d-brief/files/2014/02/shutterstock_114742003.jpg # -----I hope you are having a great day---- ——————————————— ## Munchies https://i.imgur.com/Oqi1WUJ.jpg *Here you can see an example of munchies, also lesser known as cannabis appetite. Three pieces of toast sendwich with 2 types of cheese, mayonnaise and pommes sauce, also one piece of salted crescent bread with the same ingredients.* ——————————————— **Munchies is the feeling of hunger after smoking weed, or as the [Urban dictionary](https://www.google.de/amp/s/www.urbandictionary.com/define.php%3fterm=Munchies&=true) explains it,** **_consumption of copious amounts of carbohydrates and essential polyunsaturated fatty acids after inhaling the byproduct of a combusted hemp plant._** ——————————————— ## Introduction https://i.imgur.com/0yAGtZb.jpg *_In following post I will be diving into and exploring the what, why and how of the feeling we are all too familiar with after a smoke and chill session. The Munchies. I will explore and try to summerize the science behind it and the topics associated with it._* *_Providing photos along the way of some of my own munchies and cravings. I'm not a big fan of sweets so don't expect to see photos of them here._* In most cases, the consumption of **cannabis** is followed by an intense **_feeling of hunger_**. That effect has been documented for **hundreds of years** . Having been informally called **_"munchies"_** by the English speaking people and **adopted** trough out most of the world. Clinical studies have found that **cannabis consumption** increases the **_interest in food, overall enjoyment of food and widens the food palatability_**. That effect is achieved when **THC** comes into contact with **CB1** and creates **_unusual behavior patterns in certain neurons that which are more commonly known associated with decreasing hunger_**. ——————————————— ### Health and Treatment https://i.imgur.com/tOnTTkD.jpg Studies have shown have that over **70** percent of patients administrated **THC** have shown **_an increased appetite and food appreciation_**. Compared to the **30** percent of patients given a **placebo** that did not show the same effect. The effects of munchies are used in treating and helping **cancer patients** enjoy their meals, **_especially following chemotherapy treatments_**. A healthy appetite can **enhance nutrition** and **combat weight loss**, which is a often associated **_with cancer, HIV and anorexic patients._** *_I will not go into more details about those medical conditions as they are not the focus of this. _* It basically **tricks** the brain into thinking **_that it is hungry even if you do not really feel hunger._** https://i.imgur.com/xdihdfQ.jpg ——————————————— ### THC https://upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Tetrahydrocannabinol.svg/1200px-Tetrahydrocannabinol.svg.png **TETRAHYDROCANNABINOL**, more commonly known as **THC**, is one of **_113 identified cannabinoids in cannabis_** to date. Commonly assumed to be involved in the plants **self-defense** against **_predatorial insects_**, **_ultraviolet light_** and **_environmental disasters_**. Cannabis has been scheduled on the **UN** treaty of **Psychotropic Substances** knows as the **_Convention on Psychotropic Substances_** as Schedule 1 in 1971, due to the psychoactive effects induced by THC. *Just 2 years after Woodstock. Makes you think doesn't it?* **Schedule 1** is the most restrictive. It claims that drugs with such classification **_create a serious risk to public health, having no therapeutical value_**. *_Just imagine it. They took a plant used throughout thousands of years by all kinds of civilizations from around the globe as a healing herb, and classified it as a substance with absolutely no therapeutically value._* Following the recommendation of the **WHO** (World Health Organization) it got **reclassified as Schedule 2** in 1991. Since then the world is **_slowly coming around_**. A lot of places in the world are legalizing cannabis not only for **therapeutical purposes** but for **recreational purposes** as well. Starting with **Uruguay** in **2013**. *_Before you pack your begs and decide you next holiday, you should know that Cannabis is only legal to residents of Uruguay who are 18 years or older. Prohibited to foreigner. There is also the fact that you have to be registered with the authorities._* South Africa followed in 2018 next with legalization and Canada being its newest member since 2018 as well. I belive that soon, throughout the next years many other countries could follow their lead. ——————————————— ### CB1 https://upload.wikimedia.org/wikipedia/commons/b/bc/Cannabinoid_CB1_Receptor.png *_(Oddly look like party tapes, doesn't it?)_* Cannabinoid receptor type 1 more commonly known as CB1 is a CBD receptor. It partially bound to the THC and start to act in slightly different ways. Some of those ways increase appetite trough mechanisms such as: -**mTOR-** Activating the mammalian target of rapamycin -**POMCs-** Activating a subset of neurons called proopiomelanocortin neurons -**PYY-** Decreasing your levels of peptide tyrosine tyrosine They can be found in areas such as the: -**Limbic forebrain**, where it enhance food palatability. Meaning, more things taste better. -**Stomach and small intestines**, which control an appetite stimulating hormone called ghrelin. -**Basal ganglia** where it enhances eating pleasure. -**Hypothalamus and rhombencephalon**, sections of the brain that help regulate food intake. ——————————————— https://i.imgur.com/SOtTTrh.jpg As CB1 increases the appetite it is only logical to belive that blocking it cause the opposite effect. By blocking CB1 we increase the production of adiponectin, which is an anti-inflammatory hormone negatively associated with obesity. ——————————————— [Image 1 Source](http://blogs.discovermagazine.com/d-brief/files/2014/02/shutterstock_114742003.jpg) [Image 2 Source](https://upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Tetrahydrocannabinol.svg/1200px-Tetrahydrocannabinol.svg.png) [Image 3 Source](https://upload.wikimedia.org/wikipedia/commons/b/bc/Cannabinoid_CB1_Receptor.png) # -----------The End----------- Do you feel like your vote is the size of trichome? That your account will never grow bigger? You can join our small, still in beta Discord community [CryptoSmokers](https://discord.gg/TJrXD2s); but only if you tend to post regular, interesting, unique, authentic and genuine material on Smoke.io. 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